Investigating the Impact of Crohn’s Disease on the Bioaccessibility of a Lipid-Based Formulation with an In Vitro Dynamic Gastrointestinal Model-Reference-Cited by-同舟云学术

Investigating the Impact of Crohn’s Disease on the Bioaccessibility of a Lipid-Based Formulation with an In Vitro Dynamic Gastrointestinal Model

Published:2021-03-03 Issue:4 Volume:18 Page:1530-1543
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Effinger Angela¹,McAllister Mark²,Tomaszewska Irena³,O’Driscoll Caitriona M.⁴,Taylor Mark³,Gomersall Steve³,Heaton James³,Smith Kieran L.³,Sarcevica Inese³,Young Sam L.²,Fotaki Nikoletta¹^ORCID

Affiliation:

1. Department of Pharmacy and Pharmacology, University of Bath, Claverton Down, Bath BA2 7AY, U.K.

2. Pfizer Drug Product Design, Sandwich CT13 9NJ, U.K.

3. Pfizer Analytical Research and Development, Sandwich CT13 9NJ, U.K.

4. School of Pharmacy, University College Cork, Cavanagh Pharmacy Building, Cork T12 YT20, Ireland

Funder

H2020 Marie Sklodowska-Curie Actions

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.0c00807

Reference73 articles.

1. The burden of inflammatory bowel disease in Europe

2. The Pathogenesis of Extraintestinal Manifestations: Implications for IBD Research, Diagnosis, and Therapy

3. Medication use among inflammatory bowel disease patients: excessive consumption of antidepressants and analgesics

4. Impact of gastrointestinal disease states on oral drug absorption – implications for formulation design – a PEARRL review

5. Impaired Gastric Acid and Pancreatic Enzyme Secretion in Patients With Crohn’s Disease May be a Consequenece of a Poor Nutritional State

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