Application of an in Vitro Blood–Brain Barrier Model in the Selection of Experimental Drug Candidates for the Treatment of Huntington’s Disease
Author:
Affiliation:
1. CHDI Management, CHDI Foundation, Center Drive Los Angeles 6080, California, United States
Funder
CHDI Foundation, Inc.
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Pharmaceutical Science,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.9b00042
Reference61 articles.
1. Huntington's disease: a clinical review
2. Primary cultures of brain microvessel endothelial cells: a valid and flexible model to study drug transport through the blood–brain barrier in vitro
3. A detailed method for preparation of a functional and flexible blood–brain barrier model using porcine brain endothelial cells
4. Patented In Vitro Blood-Brain Barrier Models in CNS Drug Discovery
5. Permeability Studies on In Vitro Blood–Brain Barrier Models: Physiology, Pathology, and Pharmacology
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