Oral Delivery of a Nanocrystal Formulation of Schisantherin A with Improved Bioavailability and Brain Delivery for the Treatment of Parkinson’s Disease-Reference-Cited by-同舟云学术

Oral Delivery of a Nanocrystal Formulation of Schisantherin A with Improved Bioavailability and Brain Delivery for the Treatment of Parkinson’s Disease

Published:2016-10-21 Issue:11 Volume:13 Page:3864-3875
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Chen Tongkai¹,Li Chuwen¹,Li Ye¹,Yi Xiang²,Lee Simon Ming-Yuen¹,Zheng Ying¹

Affiliation:

1. State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau, China

2. Division of Molecular Pharmaceutics, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States

Funder

Fundo para o Desenvolvimento das Ciências e da Tecnologia

Research Fund, Universidade de Macau

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.6b00644

Reference36 articles.

1. World Health Organization.Neurological disorders: public health challenges;WHO Press:Geneva, Switzerland, 2006; pp140–148.

2. The Chinese herbal formula Liuwei dihuang protects dopaminergic neurons against Parkinson's toxin through enhancing antioxidative defense and preventing apoptotic death