Tailoring Release Profiles of BCS Class II Drugs Using Controlled Release Amorphous Solid Dispersion Beads with Membrane-Reservoir Design: Effect of Pore Former and Coating Levels
Author:
Affiliation:
1. Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario M5S 3M2, Canada
2. Thermo Fisher Scientific, Mississauga, Ontario L5N 7K9, Canada
Funder
Natural Sciences and Engineering Research Council of Canada
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Pharmaceutical Science,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.1c00623
Reference44 articles.
1. Successful oral delivery of poorly water-soluble drugs both depends on the intraluminal behavior of drugs and of appropriate advanced drug delivery systems
2. Expanding the Application and Formulation Space of Amorphous Solid Dispersions with KinetiSol®: a Review
3. Supersaturating drug delivery systems: The potential of co-amorphous drug formulations
4. Investigation of the effects of process variables on derived properties of spray dried solid-dispersions using polymer based response surface model and ensemble artificial neural network models
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1. An emerging terpolymeric nanoparticle pore former as an internal recrystallization inhibitor of celecoxib in controlled release amorphous solid dispersion beads: Experimental studies and molecular dynamics analysis;Acta Pharmaceutica Sinica B;2024-06
2. The impact of applying an additional polymer coating on high drug-loaded amorphous solid dispersions layered onto pellets;International Journal of Pharmaceutics;2023-01
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