In Vivo Insulin Peptide Autoantigen Delivery by Mannosylated Sodium Alginate Nanoparticles Delayed but Could Not Prevent the Onset of Type 1 Diabetes in Nonobese Diabetic Mice

Author:

Qu Yue1,Shi Hang1,Liu Mohan1,Zhang Mingming1ORCID,Wang Hai1,Pang Liyun1,Zhang Chuangnian1,Kong Deling2ORCID,Li Chen1ORCID

Affiliation:

1. Tianjin Key Laboratory of Biomedical Materials, Biomedical Barriers Research Center, Institute of Biomedical Engineering, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300192, China

2. Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Sciences, State Key Laboratory of Medicinal Chemical Biology, Collaborative Innovation Centre of Chemical Science and Engineering, and National Institute of Functional Materials, Nankai University, Tianjin 300071, China

Funder

National Natural Science Foundation of China

Tianjin Research Program for Distinguished Young Scholar

Non-profit Central Research Institute Fund of the Chinese Academy of Medical Sciences

Tianjin Association for Science & Technology Youth Talent Promotion Project

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

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