Effect of Coadministered Water on the In Vivo Performance of Oral Formulations Containing N-Acetylcysteine: An In Vitro Approach Using the Dynamic Open Flow-Through Test Apparatus
Author:
Affiliation:
1. Department of Biopharmaceutics and Pharmaceutical Technology, Institute of Pharmacy, University of Greifswald, Felix-Hausdorff-Straße 3, 17487 Greifswald, Germany
2. HEXAL AG, Industriestraße 25, D-83607 Holzkirchen, Germany
Funder
European Commission
European Federation of Pharmaceutical Industries and Associations
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Pharmaceutical Science,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.7b00763
Reference30 articles.
1. Quantification of Gastrointestinal Liquid Volumes and Distribution Following a 240 mL Dose of Water in the Fasted State
2. Predicting the human in vivo performance of different oral capsule shell types using a novel in vitro dynamic gastric model
3. A Multicompartmental Dynamic Computer-controlled Model Simulating the Stomach and Small Intestine
4. A Dynamic Artificial Gastrointestinal System for Studying the Behavior of Orally Administered Drug Dosage Forms Under Various Physiological Conditions
5. A Novel in Vitro and Numerical Analysis of Shear-Induced Drug Release from Extended-Release Tablets in the Fed Stomach
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