Freeze-Induced Phase Transition and Local Pressure in a Phospholipid/Water System: Novel Insights Were Obtained from a Time/Temperature Resolved Synchrotron X-ray Diffraction Study-Reference-Cited by-同舟云学术

Freeze-Induced Phase Transition and Local Pressure in a Phospholipid/Water System: Novel Insights Were Obtained from a Time/Temperature Resolved Synchrotron X-ray Diffraction Study

Published:2023-10-27 Issue:11 Volume:20 Page:5790-5799
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Rodrigues Miguel A.¹,Matsarskaia Olga²^ORCID,Rego Pedro¹,Geraldes Vitor¹,Connor Lauren E.³⁴,Oswald Iain D. H.³^ORCID,Sztucki Michael⁵^ORCID,Shalaev Evgenyi⁶^ORCID

Affiliation:

1. Centro de Química Estrutural, Instituto Superior Tecnico, University of Lisbon, Lisbon 1049-001, Portugal

2. Institut Laue−Langevin, 71 Avenue des Martyrs, Grenoble 38000, France

3. Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow G4 0RE, U.K.

4. Collaborative International Research Programme, University of Strathclyde and Nanyang Technological University, Singapore, Technology Innovation Centre, Glasgow G1 1RD, U.K.

5. European Synchrotron Radiation Facility, Grenoble Cedex 9 38043, France

6. Abbvie Inc., 2525 Dupont Drive, Irvine, California 92612, United States

Funder

Engineering and Physical Sciences Research Council

University of Strathclyde

Nanyang Technological University

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.3c00657

Reference44 articles.

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2. Development of a freeze-stable formulation for vaccines containing aluminum salt adjuvants

3. Frozen-State Storage Stability of a Monoclonal Antibody: Aggregation is Impacted by Freezing Rate and Solute Distribution

4. Freezing of Biologicals Revisited: Scale, Stability, Excipients, and Degradation Stresses