Inhaled JAK Inhibitor GDC-0214 Nanoaggregate Powder Exhibits Improved Pharmacokinetic Profile in Rats Compared to the Micronized Form: Benefits of Thin Film Freezing-Reference-Cited by-同舟云学术

Inhaled JAK Inhibitor GDC-0214 Nanoaggregate Powder Exhibits Improved Pharmacokinetic Profile in Rats Compared to the Micronized Form: Benefits of Thin Film Freezing

Published:2024-01-12 Issue:2 Volume:21 Page:564-580
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Moon Chaeho¹^ORCID,Sahakijpijarn Sawittree¹²,Maier Esther Y.³,Taft David R.⁴,Jara Miguel O.¹,Praphawatvet Tuangrat¹,Manandhar Rachana²,Shetty Nivedita⁵,Lubach Joseph⁵^ORCID,Narang Ajit⁵^ORCID,Nagapudi Karthik⁵,Williams Robert O.¹^ORCID

Affiliation:

1. Division of Molecular Pharmaceutics and Drug Delivery, College of Pharmacy, The University of Texas at Austin, Austin, Texas 78712, United States

2. TFF Pharmaceuticals, Inc., Austin, Texas 78753, United States

3. Drug Dynamics Institute, College of Pharmacy, The University of Texas at Austin, Austin, Texas 78723, United States

4. Division of Pharmaceutical Sciences, Long Island University, Brooklyn, New York 11201, United States

5. Genentech, Inc., South San Francisco, California 94080, United States

Funder

Genentech

TFF Pharmaceuticals, Inc.

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.3c00719

Reference64 articles.

1. Most Recent National Asthma Data. Centers for Disease Control and Prevention: Centers for Disease Control and Prevention; 2022; Vol. 2022.

2. Uncontrolled asthma: A review of the prevalence, disease burden and options for treatment

3. Uniform definition of asthma severity, control, and exacerbations: Document presented for the World Health Organization Consultation on Severe Asthma

4. Asthma control and disease burden in patients with asthma and allergic comorbidities

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1. Correction to “Inhaled JAK Inhibitor GDC-0214 Nanoaggregate Powder Exhibits Improved Pharmacokinetic Profile in Rats Compared to the Micronized Form: Benefits of Thin Film Freezing”;Molecular Pharmaceutics;2024-04-25