Prediction of Compound Plasma Concentration–Time Profiles in Mice Using Random Forest-Reference-Cited by-同舟云学术

Prediction of Compound Plasma Concentration–Time Profiles in Mice Using Random Forest

Published:2023-04-25 Issue:6 Volume:20 Page:3060-3072
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Handa Koichi¹²^ORCID,Wright Peter¹^ORCID,Yoshimura Saki²,Kageyama Michiharu²,Iijima Takeshi²,Bender Andreas¹^ORCID

Affiliation:

1. Centre for Molecular Informatics, Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, U.K.

2. Toxicology & DMPK Research Department, Teijin Institute for Bio-medical Research, Teijin Pharma Limited, 4-3-2 Asahigaoka, Hino-shi, Tokyo 191-8512, Japan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.3c00071

Reference41 articles.

1. The right compound in the right assay at the right time: an integrated discovery DMPK strategy

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4. Quantitative Structure–Activity Relationship Models of Clinical Pharmacokinetics: Clearance and Volume of Distribution

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