Gut Microbiota-Mediated Bile Acid Transformations Alter the Cellular Response to Multidrug Resistant Transporter Substrates in Vitro: Focus on P-glycoprotein-Reference-Cited by-同舟云学术

Gut Microbiota-Mediated Bile Acid Transformations Alter the Cellular Response to Multidrug Resistant Transporter Substrates in Vitro: Focus on P-glycoprotein

Published:2018-11-02 Issue:12 Volume:15 Page:5711-5727
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Enright Elaine F.¹^ORCID,Govindarajan Kalaimathi,Darrer Rebecca,MacSharry John,Joyce Susan A.,Gahan Cormac G. M.¹

Affiliation:

1. School of Pharmacy, ‡APC Microbiome Ireland, §School of Biochemistry and Cell Biology, ∥School of Microbiology, ⊥School of Medicine, University College Cork, Cork, Ireland

Funder

Irish Research Council

Science Foundation Ireland

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.8b00875

Reference52 articles.

1. Impact of Gut Microbiota-Mediated Bile Acid Metabolism on the Solubilization Capacity of Bile Salt Micelles and Drug Solubility

2. Novel oral absorption system containing polyamines and bile salts enhances drug transport via both transcellular and paracellular pathways across Caco-2 cell monolayers