Understanding Particle Formation: Solubility of Free Fatty Acids as Polysorbate 20 Degradation Byproducts in Therapeutic Monoclonal Antibody Formulations-Reference-Cited by-同舟云学术

Understanding Particle Formation: Solubility of Free Fatty Acids as Polysorbate 20 Degradation Byproducts in Therapeutic Monoclonal Antibody Formulations

Published:2015-10-13 Issue:11 Volume:12 Page:3792-3804
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Doshi Nidhi¹,Demeule Barthélemy¹,Yadav Sandeep¹

Affiliation:

1. Late Stage Pharmaceutical Development, Genentech Inc., 1 DNA Way, South San Francisco, California 94080, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.5b00310

Reference29 articles.

1. Surfactant-Stabilized Protein Formulations: A Review of Protein-Surfactant Interactions and Novel Analytical Methodologies

2. Tween protects recombinant human growth hormone against agitation-induced damage via hydrophobic interactions

3. Influence of surfactants upon protein/peptide adsorption to glass and polypropylene

4. Adsorption Behavior of a Surfactant and a Monoclonal Antibody to Sterilizing-Grade Filters

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