A Human Immortalized Cell-Based Blood–Brain Barrier Triculture Model: Development and Characterization as a Promising Tool for Drug−Brain Permeability Studies-Reference-Cited by-同舟云学术

A Human Immortalized Cell-Based Blood–Brain Barrier Triculture Model: Development and Characterization as a Promising Tool for Drug−Brain Permeability Studies

Published:2019-10-01 Issue:11 Volume:16 Page:4461-4471
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Ito Ryo¹^ORCID,Umehara Kenta²,Suzuki Shota²,Kitamura Keita²,Nunoya Ken-ichi¹,Yamaura Yoshiyuki¹,Imawaka Haruo¹,Izumi Saki³^ORCID,Wakayama Naomi³,Komori Takafumi³,Anzai Naohiko⁴,Akita Hidetaka²^ORCID,Furihata Tomomi⁵

Affiliation:

1. Pharmacokinetic Research Laboratories, Ono Pharmaceutical Co., Ltd., Osaka 618-8585, Japan

2. Laboratory of DDS Design and Drug Disposition, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba 260-8670, Japan

3. Drug Metabolism and Pharmacokinetics Tsukuba, Tsukuba Research Laboratories, Eisai Co., Ltd., Ibaraki 300-2635, Japan

4. Department of Pharmacology, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan

5. Department of Clinical Pharmacy & Experimental Therapeutics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Tokyo 192-0392, Japan

Funder

Japan Agency for Medical Research and Development

Mochida Memorial Foundation for Medical and Pharmaceutical Research

Eisai Co.

Ono Pharmaceutical Co.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.9b00519

Reference48 articles.