Incorporation of Complexation into a Coamorphous System Dramatically Enhances Dissolution and Eliminates Gelation of Amorphous Lurasidone Hydrochloride-Reference-Cited by-同舟云学术

Incorporation of Complexation into a Coamorphous System Dramatically Enhances Dissolution and Eliminates Gelation of Amorphous Lurasidone Hydrochloride

Published:2019-12-03 Issue:1 Volume:17 Page:84-97
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Heng Weili,Su Meiling,Cheng Hao,Shen Peiya,Liang Shujun,Zhang Linghe¹,Wei Yuanfeng,Gao Yuan,Zhang Jianjun,Qian Shuai^ORCID

Affiliation:

1. Department of Chemistry, Smith College, Northampton, Massachusetts 01063, United States

Funder

Ministry of Education of the People's Republic of China

Government of Jiangsu Province

National Natural Science Foundation of China

Priority Academic Program Development of Jiangsu Higher Education Institutions

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.9b00772

Reference83 articles.

1. Bridging solubility between drug discovery and development

2. Solubility advantage of amorphous pharmaceuticals: I. A thermodynamic analysis

3. Better understanding of dissolution behaviour of amorphous drugs by in situ solid-state analysis using Raman spectroscopy

4. Stability of Amorphous Pharmaceutical Solids: Crystal Growth Mechanisms and Effect of Polymer Additives

5. Molecular Dynamics and Physical Stability of Amorphous Anti-Inflammatory Drug: Celecoxib

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