Treatment of Orthotopic U251 Human Glioblastoma Multiforme Tumors in NRG Mice by Convection-Enhanced Delivery of Gold Nanoparticles Labeled with the β-Particle-Emitting Radionuclide, 177Lu

Author:

Georgiou Constantine J.1ORCID,Cai Zhongli1ORCID,Alsaden Noor1,Cho Hyungjun2,Behboudi Minou1,Winnik Mitchell A.2ORCID,Rutka James T.34,Reilly Raymond M.156ORCID

Affiliation:

1. Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, 144 College Street, Toronto, OntarioM5S 3M2, Canada

2. Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, OntarioM5S 3H6, Canada

3. Division of Neurosurgery, The Hospital for Sick Children, 555 University Avenue, Toronto, OntarioM5G 1X8, Canada

4. Division of Neurosurgery, Department of Surgery, Temerty Faculty of Medicine, University of Toronto, 149 College Street, Toronto, OntarioM5T 1P5, Canada

5. Department of Medical Imaging, Temerty Faculty of Medicine, University of Toronto, Toronto, OntarioM5S 1A8, Canada

6. Joint Department of Medical Imaging and Princess Margaret Cancer Centre, University Health Network, Toronto, OntarioM5G 2C1, Canada

Funder

University of Toronto

Terry Fox Foundation

Brain Tumour Foundation of Canada

Natural Sciences and Engineering Research Council of Canada

Canadian Cancer Society

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

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