Transnasal Delivery of the Peptide Agonist Specific to Neuromedin-U Receptor 2 to the Brain for the Treatment of Obesity

Author:

Tanaka Akiko12,Takayama Kentaro3,Furubayashi Tomoyuki2,Mori Kenji4,Takemura Yuki1,Amano Mayumi1,Maeda Chiaki1,Inoue Daisuke5ORCID,Kimura Shunsuke6,Kiriyama Akiko6,Katsumi Hidemasa1,Miyazato Mikiya4,Kangawa Kenji4,Sakane Toshiyasu2ORCID,Hayashi Yoshio3ORCID,Yamamoto Akira1

Affiliation:

1. Department of Biopharmaceutics, Kyoto Pharmaceutical University, Yamashina, Kyoto 607-8414, Japan

2. Department of Pharmaceutical Technology, Kobe Pharmaceutical University, Motoyamakita-machi 4-19-1, Higashinada, Kobe 658-8558, Japan

3. Department of Medicinal Chemistry, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan

4. Department of Biochemistry, National Cerebral and Cardiovascular Center Research Institute, 5-7-1 Fujishirodai, Suita, Osaka 565-8565, Japan

5. College of Pharmaceutical Sciences, Ritsumeikan University, 1-1-1 Noji-higashi, Kusatsu, Shiga 525-8577, Japan

6. Faculty of Pharmaceutical Sciences, Doshisha Women’s College of Liberal Arts, Kodo, Kyotanabe, Kyoto 610-0395, Japan

Funder

Japan Society for the Promotion of Science

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

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