Investigation of Praziquantel/Cyclodextrin Inclusion Complexation by NMR and LC-HRMS/MS: Mechanism, Solubility, Chemical Stability, and Degradation Products-Reference-Cited by-同舟云学术

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Investigation of Praziquantel/Cyclodextrin Inclusion Complexation by NMR and LC-HRMS/MS: Mechanism, Solubility, Chemical Stability, and Degradation Products

Published:2021-10-21 Issue:11 Volume:18 Page:4210-4223
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Špehar Tatjana Kezele¹,Pocrnić Marijana²,Klarić David²,Bertoša Branimir²^ORCID,Čikoš Ana³,Jug Mario⁴^ORCID,Padovan Jasna¹,Dragojević Snježana¹,Galić Nives²^ORCID

Affiliation:

1. Fidelta Ltd., Prilaz baruna Filipovića 29, 10 000 Zagreb, Croatia

2. Department of Chemistry, Faculty of Science, University of Zagreb, Horvatovac 102a, 10 000 Zagreb, Croatia

3. Institute Ruđer Bošković, Bijenička cesta 54, 10 000 Zagreb, Croatia

4. Department of Pharmaceutical Technology, Faculty of Pharmacy and Biochemistry, University of Zagreb, A. Kovačića 1, 10 000 Zagreb, Croatia

Funder

European Regional Development Fund

Ministarstvo znanosti i obrazovanja

Croatian Government

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.1c00716

Reference40 articles.

1. One hundred years of neglect in paediatric schistosomiasis

2. The little we know about the pharmacokinetics and pharmacodynamics of praziquantel (racemate and R-enantiomer)

3. Development of flexible and dispersible oral formulations containing praziquantel for potential schistosomiasis treatment of pre-school age children

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1. 17-β-Estradiol—β-Cyclodextrin complex as an aqueous solution: Structural and physicochemical characterization supported by MM and QM calculations;Journal of Molecular Structure;2024-10

2. Inclusion complexes of loratadine with β-cyclodextrin and its derivatives in solution. Integrated spectroscopic, thermodynamic and computational studies;Journal of Molecular Liquids;2024-09

3. Inclusion complexes of nabumetone with β-cyclodextrins: Spectroscopic, spectrometric and calorimetric studies in solution;Journal of Molecular Liquids;2024-03

4. Preparation and evaluation of fast-dissolving albendazole sulfoxide and praziquantel-loaded polyvinylpyrrolidone nanofiber films by electrospinning;Journal of Drug Delivery Science and Technology;2024-02

5. Product contamination during mechanochemical synthesis of praziquantel co-crystal, polymeric dispersion and cyclodextrin complex;Journal of Pharmaceutical and Biomedical Analysis;2024-01

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