Identification of 5-Carboxyfluorescein as a Probe Substrate of SLC46A3 and Its Application in a Fluorescence-Based In Vitro Assay Evaluating the Interaction with SLC46A3-Reference-Cited by-同舟云学术

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Identification of 5-Carboxyfluorescein as a Probe Substrate of SLC46A3 and Its Application in a Fluorescence-Based In Vitro Assay Evaluating the Interaction with SLC46A3

Published:2022-12-02 Issue:1 Volume:20 Page:491-499
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Tomabechi Ryuto¹,Miyasato Miki¹,Sato Taeka¹,Takada Tappei²,Higuchi Kei¹,Kishimoto Hisanao¹,Shirasaka Yoshiyuki³^ORCID,Inoue Katsuhisa¹^ORCID

Affiliation:

1. Department of Biopharmaceutics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432-1, Horinouchi, Hachioji, Tokyo192-0392, Japan

2. Department of Pharmacy, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo113-8655, Japan

3. Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kakuma-machi, Kanazawa920-1192, Japan

Funder

Japan Society for the Promotion of Science

Japan Science and Technology Agency

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.2c00741

Reference35 articles.

1. Critical considerations in the formulation development of parenteral biologic drugs

2. Liposomal Targeting Modifies Endosomal Escape: Design and Mechanistic Implications

3. Recent advances in drug delivery systems for enhancing drug penetration into tumors

4. Carriers Break Barriers in Drug Delivery: Endocytosis and Endosomal Escape of Gene Delivery Vectors

5. Mechanisms of Endocytosis

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1. The Use of Carboxyfluorescein Reveals the Transport Function of MCT6/SLC16A5 Associated with CD147 as a Chloride-Sensitive Organic Anion Transporter in Mammalian Cells;Journal of Pharmaceutical Sciences;2023-12

2. Macrolide and Ketolide Antibiotics Inhibit the Cytotoxic Effect of Trastuzumab Emtansine in HER2-Positive Breast Cancer Cells: Implication of a Potential Drug–ADC Interaction in Cancer Chemotherapy;Molecular Pharmaceutics;2023-11-16

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