Effect of a Common Genetic Variant (p.V444A) in the Bile Salt Export Pump on the Inhibition of Bile Acid Transport by Cholestatic Medications-Reference-Cited by-同舟云学术

Effect of a Common Genetic Variant (p.V444A) in the Bile Salt Export Pump on the Inhibition of Bile Acid Transport by Cholestatic Medications

Published:2019-01-04 Issue:3 Volume:16 Page:1406-1411
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Ali Izna¹^ORCID,Khalid Seher¹,Stieger Bruno²,Brouwer Kim L. R.¹^ORCID

Affiliation:

1. Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States

2. Department of Clinical Pharmacology and Toxicology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland

Funder

Schweizerischer Nationalfonds zur F?rderung der Wissenschaftlichen Forschung

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.8b01124

Reference39 articles.

1. Bile Acids as Regulators of Hepatic Lipid and Glucose Metabolism

2. Bile-acid-induced cell injury and protection

3. Functional expression of the canalicular bile salt export pump of human liver

4. The human bile salt export pump: Characterization of substrate specificity and identification of inhibitors

5. Benign Recurrent Intrahepatic Cholestasis Associated With Mutations of the Bile Salt Export Pump

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