Contribution of Phe112, Ser114, and Tyr115 to Drug-Binding Selectivity in the A Variant of α<sub>1</sub>-Acid Glycoprotein-Reference-Cited by-同舟云学术

Contribution of Phe112, Ser114, and Tyr115 to Drug-Binding Selectivity in the A Variant of α₁-Acid Glycoprotein

Published:2024-07-01 Issue:8 Volume:21 Page:4038-4046
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Nakamura Yuka¹^ORCID,Watanabe Hiroshi²^ORCID,Nakamura Teruya³,Chirifu Mami³,Ishiodori Kana¹,Imafuku Tadashi¹,Maeda Hitoshi¹,Kobashigawa Yoshihiro⁴,Morioka Hiroshi⁴,Maruyama Toru¹

Affiliation:

1. Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Chuo-ku, Kumamoto 862-0973, Japan

2. Department of Clinical Pharmacy and Therapeutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Chuo-ku, Kumamoto 862-0973, Japan

3. Department of Structural Biology, Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Chuo-ku, Kumamoto 862-0973, Japan

4. Department of Analytical and Biophysical Chemistry, Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Chuo-ku, Kumamoto 862-0973, Japan

Funder

Japan Society for the Promotion of Science

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.4c00428

Reference22 articles.

1. Halsall, H. B. In Structural Aspects of Alpha1-Acid Glycoprotein and Its Interaction, Proceedings of the International Symposium on Serum Albumin and α1-Acid Glycoprotein, Kumamoto, Japan, 2000; pp 45–54.

2. The plasma protein binding of basic drugs.

3. HUMAN ALPHA-1-GLYCOPROTEIN AND ITS INTERACTIONS WITH DRUGS†,‡

4. Plasma protein binding of drugs after severe burn injury