Usefulness of Optimized Human Fecal Material in Simulating the Bacterial Degradation of Sulindac and Sulfinpyrazone in the Lower Intestine
Author:
Affiliation:
1. Department of Pharmacy, National and Kapodistrian University of Athens, 157 84 Zografou, Greece
2. Janssen Pharmaceutica NV, B-2340 Beerse, Belgium
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Pharmaceutical Science,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.2c00224
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1. Evaluation of an in vitro faecal degradation method for early assessment of the impact of colonic degradation on colonic absorption in humans
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5. The gastrointestinal microbiota as a site for the biotransformation of drugs
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