CysLTR1 Blockage Ameliorates Liver Injury Caused by Aluminum-Overload via PI3K/AKT/mTOR-Mediated Autophagy Activation in Vivo and in Vitro-Reference-Cited by-同舟云学术

CysLTR1 Blockage Ameliorates Liver Injury Caused by Aluminum-Overload via PI3K/AKT/mTOR-Mediated Autophagy Activation in Vivo and in Vitro

Published:2018-04-10 Issue:5 Volume:15 Page:1996-2006
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Hu Congli¹,Yang Junqing¹^ORCID,He Qin²,Luo Ying¹,Chen Zhihao¹,Yang Lu¹,Yi Honggang¹,Li Huan¹,Xia Hui¹,Ran Dongzhi¹,Yang Yang¹,Zhang Jiahua¹,Li Yuke¹,Wang Hong¹^ORCID

Affiliation:

1. Department of Pharmacology, Chongqing Medical University, the Key Laboratory of Biochemistry and Molecular Pharmacology, Chongqing 400016, China

2. Department of Hepatobiliary Surgery, First Affiliated Hospital, Chongqing Medical University, Chongqing 400016, China

Funder

Chongqing Municipal Public Health Bureau, Chongqing People's Municipal Government

Chongqing Science Technology Commission of China

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.8b00121

Reference47 articles.

1. Aluminium neurotoxicity: neurobehavioural and oxidative aspects

2. Histopathological Changes in Rat Liver After A Single High Dose of Aluminium

3. Propolis prevents aluminium-induced genetic and hepatic damages in rat liver

4. Protective effect of selenium on aluminium-induced oxidative stress in mouse liver in vivo

5. Metal Ion Imbalance-Related Oxidative Stress Is Involved in the Mechanisms of Liver Injury in a Rat Model of Chronic Aluminum Exposure

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