Validation of Thiosemicarbazone Compounds as P-Glycoprotein Inhibitors in Human Primary Brain–Blood Barrier and Glioblastoma Stem Cells-Reference-Cited by-同舟云学术

Validation of Thiosemicarbazone Compounds as P-Glycoprotein Inhibitors in Human Primary Brain–Blood Barrier and Glioblastoma Stem Cells

Published:2019-06-20 Issue:8 Volume:16 Page:3361-3373
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Salaroglio Iris Chiara¹,Abate Carmen²^ORCID,Rolando Barbara³^ORCID,Battaglia Luigi³,Gazzano Elena¹,Colombino Elena⁴,Costamagna Costanzo¹,Annovazzi Laura⁵,Mellai Marta⁶,Berardi Francesco²,Capucchio Maria Teresa⁴,Schiffer Davide⁷,Riganti Chiara¹^ORCID

Affiliation:

1. Dipartimento di Oncologia, Università di Torino, via Santena 5/bis, 10126 Torino, Italy

2. Dipartimento di Farmacia-Scienze del Farmaco, Università di Bari “Aldo Moro”, Via Orabona 4, 70125 Bari, Italy

3. Dipartimento di Scienza e Tecnologia del Farmaco, Università di Torino, via Pietro Giuria 9, 10125 Torino, Italy

4. Dipartimento di Scienze Veterinarie, Università di Torino, Largo Braccini 2, 10095 Grugliasco, Italy

5. Centro Ricerche, Fondazione Policlinico di Monza, via Pietro Micca 29, 13100 Vercelli, Italy

6. Dipartimento di Scienze della Salute, Università del Piemonte Orientale, corso Mazzini 18, 28100 Novara, Italy

7. Dipartimento di Neuroscienze, Università di Torino, via Cherasco 15, 10126 Torino, Italy

Funder

Ministero dell?Istruzione, dell?Universit? e della Ricerca

Associazione Italiana per la Ricerca sul Cancro

Fondazione Italiana per la Ricerca sul Cancro

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.9b00018

Reference43 articles.

1. Molecular targeting of glioblastoma: Drug discovery and therapies

2. Success and Failures of Combined Modalities in Glioblastoma Multiforme: Old Problems and New Directions

3. Chemoresistance of glioblastoma cancer stem cells - much more complex than expected

4. The role of glioma stem cells in chemotherapy resistance and glioblastoma multiforme recurrence

5. Temozolomide competes for P-glycoprotein and contributes to chemoresistance in glioblastoma cells

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