Development of an Orthogonal Tie2 Ligand Resistant to Inhibition by Ang2-Reference-Cited by-同舟云学术

Development of an Orthogonal Tie2 Ligand Resistant to Inhibition by Ang2

Published:2018-07-23 Issue:9 Volume:15 Page:3962-3968
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Issa Eyad¹,Moss Andrew J¹,Fischer Marlies¹,Kang Mandeep¹,Ahmed Sultan¹,Farah Hussein¹,Bate Neil¹,Giakomidi Despoina¹,Brindle Nicholas PJ¹^ORCID

Affiliation:

1. Department of Cardiovascular Sciences and Department of Molecular and Cell Biology, University of Leicester, Henry Wellcome Building, Lancaster Road, Leicester LE1 7RH, U.K.

Funder

British Heart Foundation

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.8b00409

Reference33 articles.

1. Control of vascular morphogenesis and homeostasis through the angiopoietin–Tie system

2. Functional Significance of Tie2 Signaling in the Adult Vasculature

3. Angiopoietin-1 Regulates Endothelial Cell Survival Through the Phosphatidylinositol 3′-Kinase/Akt Signal Transduction Pathway

4. Angiopoietin-1 is an apoptosis survival factor for endothelial cells

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