Phase Behavior and Crystallization Kinetics of a Poorly Water-Soluble Weakly Basic Drug as a Function of Supersaturation and Media Composition-Reference-Cited by-同舟云学术

Phase Behavior and Crystallization Kinetics of a Poorly Water-Soluble Weakly Basic Drug as a Function of Supersaturation and Media Composition

Published:2022-03-23 Issue:4 Volume:19 Page:1146-1159
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Van Duong Tu¹^ORCID,Ni Zhanglin²,Taylor Lynne S.¹^ORCID

Affiliation:

1. Department of Industrial and Physical Pharmacy, College of Pharmacy, Purdue University, West Lafayette, Indiana 47907, United States

2. Division of Quantitative Methods and Modeling, Office of Research and Standards, Office of Generic Drugs, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland 20993, United States

Funder

U.S. Food and Drug Administration

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.1c00927

Reference86 articles.

1. Pharmaceutical applications of cyclodextrins: basic science and product development

2. Strategies to Address Low Drug Solubility in Discovery and Development

3. Supersaturating Drug Delivery Systems: The Answer to Solubility-Limited Oral Bioavailability?

4. Correlation and Prediction of Mass Transport Across Membranes II: Influence of Vehicle Polarity on Flux From Solutions and Suspensions

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