Implications of Drug–Polymer Interactions on Time–Temperature–Transformation: A Tool to Assess the Crystallization Propensity in Amorphous Solid Dispersions
Author:
Affiliation:
1. Department of Pharmaceutics, College of Pharmacy, University of Minnesota, 9-177 WDH, 308 Harvard Street S.E., Minneapolis, Minnesota55455, United States
Funder
William and Mildred Peters endowment fund
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Pharmaceutical Science,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.2c01004
Reference58 articles.
1. Amorphous pharmaceutical solids: preparation, characterization and stabilization
2. Solid dispersion of poorly water‐soluble drugs: Early promises, subsequent problems, and recent breakthroughs
3. Role of the Strength of Drug–Polymer Interactions on the Molecular Mobility and Crystallization Inhibition in Ketoconazole Solid Dispersions
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