Mapping the Aggregation Kinetics of a Therapeutic Antibody Fragment-Reference-Cited by-同舟云学术

Mapping the Aggregation Kinetics of a Therapeutic Antibody Fragment

Published:2016-01-04 Issue:2 Volume:13 Page:307-319
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Chakroun Nesrine¹²,Hilton David¹²,Ahmad Shahina S.²,Platt Geoffrey W.³,Dalby Paul A.¹²

Affiliation:

1. EPSRC Centre for Innovative Manufacturing in Emergent Macromolecular Therapies, Department of Biochemical Engineering, University College London, London WC1H 0AH, U.K.

2. Department of Biochemical Engineering, University College London, London WC1H 0AH, U.K.

3. Unchained Laboratories, Unit 706, Avenue E West, Thorp Arch Estate, Wetherby LS23 7EG, U.K.

Funder

Engineering and Physical Sciences Research Council

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.5b00387

Reference64 articles.

1. Antibody fragments

2. Next generation immunotherapeutics—honing the magic bullet

3. Stability of Protein Pharmaceuticals: An Update

4. Protein aggregation—Pathways and influencing factors

5. Forced Degradation of Therapeutic Proteins

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