Cocktail of Superoxide Dismutase and Fasudil Encapsulated in Targeted Liposomes Slows PAH Progression at a Reduced Dosing Frequency

Author:

Gupta Nilesh1,Rashid Jahidur1,Nozik-Grayck Eva2,McMurtry Ivan F.3,Stenmark Kurt R.2,Ahsan Fakhrul1ORCID

Affiliation:

1. Department of Pharmaceutical Sciences, School of Pharmacy, Texas Tech University Health Sciences Center, 1300 Coulter Drive, Amarillo, Texas 79106, United States

2. Developmental Lung Biology, Cardiovascular Pulmonary Research Laboratories, Division of Pulmonary Sciences and Critical Care Medicine, Division of Pediatrics-Critical Care, Departments of Medicine and Pediatrics, University of Colorado, Denver, Anschutz Medical Campus, Aurora, Colorado 80045, United States

3. Departments of Pharmacology and Internal Medicine and the Center for Lung Biology, University of South Alabama, Mobile, Alabama 36688, United States

Funder

National Heart, Lung, and Blood Institute

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

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