Design of HIV Coreceptor Derived Peptides That Inhibit Viral Entry at Submicromolar Concentrations
Author:
Affiliation:
1. Laboratory of Bioorganic Chemistry, NIDDK, NIH, Bethesda, Maryland 20892, United States
2. Laboratory of Immunoregulation, NIAID, NIH, Bethesda, Maryland 20892, United States
Funder
National Institute of Diabetes and Digestive and Kidney Diseases
National Institute of Allergy and Infectious Diseases
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Pharmaceutical Science,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.7b00155
Reference40 articles.
1. Maraviroc (UK-427,857), a Potent, Orally Bioavailable, and Selective Small-Molecule Inhibitor of Chemokine Receptor CCR5 with Broad-Spectrum Anti-Human Immunodeficiency Virus Type 1 Activity
2. Peptides corresponding to a predictive alpha-helical domain of human immunodeficiency virus type 1 gp41 are potent inhibitors of virus infection.
3. Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry
4. Inhibitors of HIV-1 Entry
5. Peptides from Second Extracellular Loop of C-C Chemokine Receptor Type 5 (CCR5) Inhibit Diverse Strains of HIV-1
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