Characterization of a Nanovaccine Platform Based on an α1,2-Mannobiose Derivative Shows Species-non-specific Targeting to Human, Bovine, Mouse, and Teleost Fish Dendritic Cells

Author:

Pappalardo Juan Sebastian123ORCID,Salmaso Stefano4,Levchenko Tatyana S.3,Mastrotto Francesca4,Bersani Sara4,Langellotti Cecilia A.25,Vermeulen Monica56,Ghersa Federica17,Quattrocchi Valeria2,Zamorano Patricia I.25,Hartner William C.3,Toniutti Micaela3,Musacchio Tiziana3,Torchilin Vladimir P.3

Affiliation:

1. Veterinary Nanomedicine Group, Instituto de Investigaciones Forestales y Agropecuarias Bariloche (IFAB, INTA-CONICET), EEA Bariloche, Instituto Nacional de Tecnología Agropecuaria, Bote Modesta Victoria 4450, San Carlos de Bariloche, Río Negro R8403DVZ, Argentina

2. Immunology and Immunomodulators Group, Instituto de Virología e Innovaciones Tecnológicas (IVIT, INTA-CONICET), IV, Instituto Nacional de Tecnología Agropecuaria, Nicolás Repetto 2799, William Morris, Buenos Aires B1681FUU, Argentina

3. Center for Pharmaceutical Biotechnology and Nanomedicine, Northeastern University, 360 Huntington Avenue, Boston, Massachusetts 02115, United States

4. Department of Pharmaceutical and Pharmacological Sciences, School of Medicine, University of Padova, Via F. Marzolo, 5, Padova 35121, Padova, Italy

5. National Council of Scientific and Technical Research (CONICET), Avenida Rivadavia 1917, Ciudad de Buenos Aires C1033AAJ, Argentina

6. Institute of Experimental Medicine (IMEX, ANM-CONICET), Academia Nacional de Medicina, Pacheco de Melo 3081, Ciudad de Buenos Aires C1425AUM, Argentina

7. Parasitology Laboratory, Instituto de Investigaciones en Biodiversidad y Medioambiente (INIBIOMA, UNCo-CONICET) Universidad Nacional del Comahue, Quintral 1250, San Carlos de Bariloche, Río Negro R8400FRF, Argentina

Funder

Northeastern University

Instituto Nacional de Tecnolog??a Agropecuaria

Ministerio de Ciencia, Tecnolog??a e Innovaci??n Productiva

Fondo para la Investigaci??n Cient??fica y Tecnol??gica

Universit?? degli Studi di Padova

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

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