Inhomogeneous Phase Significantly Reduces Oral Bioavailability of Felodipine/PVPVA Amorphous Solid Dispersion-Reference-Cited by-同舟云学术

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Inhomogeneous Phase Significantly Reduces Oral Bioavailability of Felodipine/PVPVA Amorphous Solid Dispersion

Published:2022-12-19 Issue:1 Volume:20 Page:409-418
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Gao Di¹,Zhu Dan¹,Zhou Xue²,Dong Shuai¹,Chen Yuejie¹³^ORCID

Affiliation:

1. School of Pharmacy, Minzu University of China, 100081 Beijing, China

2. Chengdu Institute of Biology, Chinese Academy of Sciences, 610000 Chengdu, China

3. Key Laboratory of Mass Spectrometry Imaging and Metabolomics (Minzu University of China), State Ethnic Affairs Commission, 100081 Beijing, China

Funder

Central University Basic Research Fund of China

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.2c00695

Reference36 articles.

1. Pharmaceutical amorphous solid dispersion: A review of manufacturing strategies

2. The use of amorphous solid dispersions: A formulation strategy to overcome poor solubility and dissolution rate

3. Solution Behavior of PVP-VA and HPMC-AS-Based Amorphous Solid Dispersions and Their Bioavailability Implications

4. Mechanisms of increased bioavailability through amorphous solid dispersions: a review

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1. Moisture-induced limited recrystallization may not reduce the dissolution of amorphous solid dispersions: A case of nitrendipine;Journal of Industrial and Engineering Chemistry;2024-09

2. Characterization and Dissolution Mechanism of Low-Molecular-Weight Organic Acids or Inorganic Mesoporous Particle-Based Piperine Amorphous Solid Dispersions;Langmuir;2024-07-09

3. Preparation of astaxanthin‐loaded composite micelles with coaxial electrospray technology for enhanced oral bioavailability and improved antioxidation capability;Journal of the Science of Food and Agriculture;2023-11-15

4. Evaluation of microstructure, dissolution rate, and oral bioavailability of paclitaxel poloxamer 188 solid dispersion;Drug Delivery and Translational Research;2023-08-14

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