Prediction of the Contribution Ratio of a Target Metabolic Enzyme to Clearance from Chemical Structure Information-Reference-Cited by-同舟云学术

Prediction of the Contribution Ratio of a Target Metabolic Enzyme to Clearance from Chemical Structure Information

Published:2022-12-20 Issue:1 Volume:20 Page:419-426
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Watanabe Reiko¹²^ORCID,Kawata Toshio³,Ueda Shinya³,Shinbo Takumi³,Higashimori Mitsuo³,Natsume-Kitatani Yayoi¹⁴,Mizuguchi Kenji¹²

Affiliation:

1. Artificial Intelligence Center for Health and Biomedical Research, National Institutes of Biomedical Innovation, Health and Nutrition, Osaka 567-0085, Japan

2. Institute for Protein Research, Osaka University, Osaka 567-0085, Japan

3. Science Enablement Department, Data Science & Innovation Division, Research & Development, AstraZeneca K.K., Osaka 530-0011, Japan

4. Institute of Advanced Medical Sciences, Tokushima University, Tokushima 567-0085, Japan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.2c00698

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