Hydration-Induced Structural Changes in the Solid State of Protein: A SAXS/WAXS Study on Lysozyme

Author:

Phan-Xuan Tuan123ORCID,Bogdanova Ekaterina12,Millqvist Fureby Anna4,Fransson Jonas5,Terry Ann E.3,Kocherbitov Vitaly12ORCID

Affiliation:

1. Biomedical Science, Malmö University, 214 32 Malmö, Sweden

2. Biofilms Research Center for Biointerfaces, Malmö University, 214 32 Malmö, Sweden

3. Max IV Laboratory, Lund University, 224 84 Lund, Sweden

4. RISE Research Institutes of Sweden, 114 86 Stockholm, Sweden

5. SOBI Swedish Orphan Biovitrum, 112 76 Stockholm, Sweden

Funder

VINNOVA

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Reference38 articles.

1. Biopharmaceutical benchmarks 2018

2. The relation between moisture-induced aggregation and structural changes in lyophilized insulin

3. Langer, R.; Klibanov, A. M. In Moisture-induced aggregation of lyophilized proteins, Abstracts of Papers of the American Chemical Society, 1996; pp 25–Btec.

4. Moisture-induced aggregation of lyophilized proteins in the solid state

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