Oligonucleotide-Functionalized Gold Nanoparticles for Synchronous Telomerase Inhibition, Radiosensitization, and Delivery of Theranostic Radionuclides-Reference-Cited by-同舟云学术

Oligonucleotide-Functionalized Gold Nanoparticles for Synchronous Telomerase Inhibition, Radiosensitization, and Delivery of Theranostic Radionuclides

Published:2021-08-27 Issue:10 Volume:18 Page:3820-3831
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Bavelaar Bas M.¹,Song Lei¹,Jackson Mark R.²,Able Sarah¹,Tietz Ole¹,Skaripa-Koukelli Irini¹,Waghorn Philip A.³,Gill Martin R.¹^ORCID,Carlisle Robert C.⁴,Tarsounas Madalena¹,Vallis Katherine A.¹^ORCID

Affiliation:

1. Oxford Institute for Radiation Oncology, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford OX3 7DQ, U.K.

2. Institute of Cancer Sciences, Wolfson Wohl Cancer Research Centre, University of Glasgow, University Avenue, Glasgow G12 8QQ, U.K.

3. Charles River Laboratories, Elphinstone Research Centre, Elphinstone, Tranent EH33 2NE, U.K.

4. Institute of Biomedical Engineering, Department of Engineering Science, University of Oxford, Old Road Campus Research Building, Oxford OX3 7DQ, U.K.

Funder

Engineering and Physical Sciences Research Council

Cancer Research UK

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.1c00442

Reference62 articles.

1. Structure of Telomerase with Telomeric DNA

2. Structure of active dimeric human telomerase