A Transporter of Ibuprofen is Upregulated in MDCK I Cells under Hyperosmotic Culture Conditions-Reference-Cited by-同舟云学术

A Transporter of Ibuprofen is Upregulated in MDCK I Cells under Hyperosmotic Culture Conditions

Published:2016-07-25 Issue:9 Volume:13 Page:3119-3129
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Nielsen Carsten Uhd¹,Rasmussen Rune N.¹,Mo Junying²,Noori Benafsha²,Lagunas Candela²,Holm René³,Nøhr Martha K.²

Affiliation:

1. Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, Campusvej 55, DK-5230 Odense M, Denmark

2. Drug Transporters in ADME, Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark

3. Pharmaceutical Science and CMC Biologics, H. Lundbeck A/S, DK-2500 Valby, Denmark

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.6b00330

Reference29 articles.

1. WHO Model Lists of Essential Medicines;WHO:Geneva, April 2015; http://www.who.int/medicines/publications/essentialmedicines/en/(accessed March 10 2016).

2. Polarised transport of monocarboxylic acid type drugs across rat jejunum in vitro: the effect of mucolysis and ATP-depletion

3. Ibuprofen is a non-competitive inhibitor of the peptide transporter hPEPT1 (SLC15A1): possible interactions between hPEPT1 substrates and ibuprofen

4. Clinical Pharmacokinetics of Ibuprofen

5. Stereoselectivity of ibuprofen metabolism and pharmacokinetics following the administration of the racemate to healthy volunteers

Cited by 6 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Activating ligands of Uncoupling protein 1 identified by rapid membrane protein thermostability shift analysis;Molecular Metabolism;2022-08

2. Activating ligands of Uncoupling protein 1 identified by rapid membrane protein thermostability shift analysis;2022-02-03

3. Transcriptome analysis identifies activated signaling pathways and regulated ABC transporters and solute carriers after hyperosmotic stress in renal MDCK I cells;Genomics;2019-12

4. Nfat5 is involved in the hyperosmotic regulation of Tmem184b: a putative modulator of ibuprofen transport in renal MDCK I cells;FEBS Open Bio;2019-05-07

5. Toxicologic/transport properties of NCS-382, a γ-hydroxybutyrate (GHB) receptor ligand, in neuronal and epithelial cells: Therapeutic implications for SSADH deficiency, a GABA metabolic disorder;Toxicology in Vitro;2018-02