Combination Therapy with Gallium Protoporphyrin and Gallium Nitrate Exhibits Enhanced Antimicrobial Activity In Vitro and In Vivo against Methicillin-Resistant Staphylococcus aureus-Reference-Cited by-同舟云学术

Combination Therapy with Gallium Protoporphyrin and Gallium Nitrate Exhibits Enhanced Antimicrobial Activity In Vitro and In Vivo against Methicillin-Resistant Staphylococcus aureus

Published:2023-07-20 Issue:8 Volume:20 Page:4058-4070
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Choi Seoung-ryoung¹^ORCID,Talmon Geoffrey A.¹,Hearne Kenneth²,Woo Jennifer²,Truong Vu L.²,Britigan Bradley E.¹³⁴,Narayanasamy Prabagaran¹^ORCID

Affiliation:

1. Department of Pathology and Microbiology, College of Medicine, University of Nebraska Medical Center, Omaha, Nebraska 68198, United States

2. Aridis Pharmaceuticals, Los Gatos, California 95032, United States

3. Department of Internal Medicine, College of Medicine, University of Nebraska Medical Center, Omaha, Nebraska 68198, United States

4. Department of Internal Medicine and Research Service, Veterans Affairs Medical Center-Nebraska Western Iowa, Omaha, Nebraska 68105, United States

Funder

State of Nebraska

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.3c00223

Reference46 articles.

1. Staphylococcus aureus Infections: Epidemiology, Pathophysiology, Clinical Manifestations, and Management

2. The emerging problem of linezolid-resistant Staphylococcus

3. Development of Daptomycin Nonsusceptibility with Heterogeneous Vancomycin-Intermediate Resistance and Oxacillin Susceptibility in Methicillin-Resistant Staphylococcus aureus during High-Dose Daptomycin Treatment

4. PBP2a Mutations Causing High-Level Ceftaroline Resistance in Clinical Methicillin-Resistant Staphylococcus aureus Isolates

5. Metallodrugs are unique: opportunities and challenges of discovery and development

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