Myristoylation Confers Oral Bioavailability and Improves the Bioactivity of c(MyD 4–4), a Cyclic Peptide Inhibitor of MyD88-Reference-Cited by-同舟云学术

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Myristoylation Confers Oral Bioavailability and Improves the Bioactivity of c(MyD 4–4), a Cyclic Peptide Inhibitor of MyD88

Published:2019-03-12 Issue:4 Volume:16 Page:1516-1522
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Dishon Shira¹,Schumacher-Klinger Adi²,Gilon Chaim³,Hoffman Amnon²^ORCID,Nussbaum Gabriel¹^ORCID

Affiliation:

1. The Institute of Dental Sciences, Hebrew University—Hadassah Faculty of Dental Medicine, Jerusalem 91120, Israel

2. The Institute for Drug Research, Hebrew University—Hadassah Faculty of Medicine, Jerusalem 91120, Israel

3. The Institute of Chemistry, Hebrew University, Jerusalem 91120, Israel

Funder

Ministry of Economy and Industry

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.8b01180

Reference34 articles.

1. Toll-like Receptor Signaling

2. Toll-like receptor signalling

3. Pyogenic Bacterial Infections in Humans with MyD88 Deficiency

4. The Toll-Like Receptor Adaptor Proteins MyD88 and Mal/TIRAP Contribute to the Inflammatory and Destructive Processes in a Human Model of Rheumatoid Arthritis

5. MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals

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