Rifampin- and Silymarin-Mediated Pharmacokinetic Interactions of Exogenous and Endogenous Substrates in a Transgenic OATP1B Mouse Model-Reference-Cited by-同舟云学术

Rifampin- and Silymarin-Mediated Pharmacokinetic Interactions of Exogenous and Endogenous Substrates in a Transgenic OATP1B Mouse Model

Published:2024-03-26 Issue:5 Volume:21 Page:2284-2297
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Bechtold Baron J.¹^ORCID,Lynch Katherine D.¹,Oyanna Victoria O.¹,Call M. Ridge¹,Graf Tyler N.²^ORCID,Oberlies Nicholas H.²^ORCID,Clarke John D.¹^ORCID

Affiliation:

1. Department of Pharmaceutical Sciences, Washington State University, 412 E. Spokane Falls Blvd., Spokane, Washington 99202, United States

2. Department of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, North Carolina 27412, United States

Funder

National Center for Complementary and Integrative Health

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.3c01088

Reference78 articles.

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2. Multi-factorial pharmacokinetic interactions: unraveling complexities in precision drug therapy

3. Transporters as a determinant of drug clearance and tissue distribution

4. Identification and Evaluation of Clinical Substrates of Organic Anion Transporting Polypeptides 1B1 and 1B3

5. Organic Anion Transporting Polypeptide (OATP)1B1 and OATP1B3 as Important Regulators of the Pharmacokinetics of Substrate Drugs

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