Interplay of Ritonavir-Boosted Oral Cabazitaxel with the Organic Anion-Transporting Polypeptide (OATP) Uptake Transporters and Carboxylesterase 1 in Mice

Author:

Loos Nancy H.C.1ORCID,Ferreira Martins Margarida L.1ORCID,Rijmers Jamie1,de Jong Daniëlle2,Lebre Maria C.1,Tibben Matthijs2,Beijnen Jos H.123,Schinkel Alfred H.1ORCID

Affiliation:

1. Division of Pharmacology, The Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam 1066 CX, The Netherlands

2. Division of Pharmacy and Pharmacology, The Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam 1066 CX, The Netherlands

3. Faculty of Science, Department of Pharmaceutical Sciences, Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht University, Universiteitsweg 99, Utrecht 3584 CG, The Netherlands

Funder

Netherlands Cancer Institute

Publisher

American Chemical Society (ACS)

Reference41 articles.

1. Update on taxane development: new analogs and new formulations

2. FDA, U.S.F.a.D.A. Prescribing information Jevtana (cabazitaxel), 2010. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/201023lbl.pdf [cited 5-11-2022]

3. EMA. Assessment Report for Jevtana (cabazitaxel), 2011. Available from: https://www.ema.europa.eu/en/documents/assessment-report/jevtana-epar-public-assessment-report_en.pdf [cited 2022 20–11–22]

4. Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomised open-label trial

5. Preclinical Antitumor Activity of Cabazitaxel, a Semisynthetic Taxane Active in Taxane-Resistant Tumors

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