Comparative Evaluation of Dissolution Performance in a USP 2 Setup and Alternative Stirrers and Vessel Designs: A Systematic Computational Investigation-Reference-Cited by-同舟云学术

Comparative Evaluation of Dissolution Performance in a USP 2 Setup and Alternative Stirrers and Vessel Designs: A Systematic Computational Investigation

Published:2024-04-19 Issue:5 Volume:21 Page:2406-2414
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Salehi Niloufar¹²³^ORCID,Al-Gousous Jozef²⁴^ORCID,Hens Bart⁵^ORCID,Amidon Gordon L.²^ORCID,Ziff Robert M.¹^ORCID,Amidon Gregory E.²

Affiliation:

1. Department of Chemical Engineering, University of Michigan, Ann Arbor, Michigan 48109, United States

2. Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, Michigan 48109, United States

3. Synthetic Molecule Design & Development, Lilly Technology Center, Eli Lilly and Company, Indianapolis, Indiana 46221, United States

4. Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University Mainz, Mainz 55128, Germany

5. Drug Product Design, Pfizer, Sandwich CT13 9NJ, U.K.

Funder

U.S. Food and Drug Administration

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.3c01203

Reference33 articles.

1. Hierarchical Mass Transfer Analysis of Drug Particle Dissolution, Highlighting the Hydrodynamics, pH, Particle Size, and Buffer Effects for the Dissolution of Ionizable and Nonionizable Drugs in a Compendial Dissolution Vessel

2. Banco, G.; Brasseur, J.; Wang, Y.; Ailiani, A.; Neuberger, T.; Webb, A. The Relation between Peristaltic and Segmental Contraction, Mixing, and Absorption in the Small Intestine. 62nd Annual Meeting of the APS Division of Fluid Dynamics; American Physical Society, 2009.

3. Behafarid, F.; Vijayakumar, G.; Brasseur, J. G. The Interplay between Pharmaceutical Dissolution and Absorption In the Human Gut Studied with Computer Simulation. American Association of Pharmaceutical Scientists Annual Meeting, 2017.