Dissolution Mechanisms of Amorphous Solid Dispersions: Application of Ternary Phase Diagrams To Explain Release Behavior-Reference-Cited by-同舟云学术

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Dissolution Mechanisms of Amorphous Solid Dispersions: Application of Ternary Phase Diagrams To Explain Release Behavior

Published:2024-03-12 Issue:4 Volume:21 Page:1900-1918
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Deac Alexandru¹,Luebbert Christian²^ORCID,Qi Qingqing¹,Courtney Reagan M.¹,Indulkar Anura S.³,Gao Yi³,Zhang Geoff G. Z.³^ORCID,Sadowski Gabriele²^ORCID,Taylor Lynne S.¹^ORCID

Affiliation:

1. Department of Industrial and Molecular Pharmaceutics, College of Pharmacy, Purdue University, West Lafayette, Indiana 47907, United States

2. amofor GmbH, Otto-Hahn-Str. 15, 44227 Dortmund, Germany

3. Development Sciences, Research and Development, AbbVie Inc., North Chicago, Illinois 60064, United States

Funder

AbbVie

Center for Bioanalytic Metrology

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.3c01179

Reference57 articles.

1. Trends in small molecule drug properties: A developability molecule assessment perspective

2. The influence of lead discovery strategies on the properties of drug candidates

3. Innovations in Thermal Processing: Hot-Melt Extrusion and KinetiSol® Dispersing

4. Dissolution Mechanisms of Amorphous Solid Dispersions: A Close Look at the Dissolution Interface

5. Release Mechanisms of Amorphous Solid Dispersions: Role of Drug-Polymer Phase Separation and Morphology

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