Comparative Preclinical Evaluation of HYNIC-Modified Designed Ankyrin Repeat Proteins G3 for the 99mTc-Based Imaging of HER2-Expressing Malignant Tumors

Author:

Larkina Maria12ORCID,Varvashenya Ruslan12,Yuldasheva Feruza1,Plotnikov Evgenii1,Bezverkhniaia Ekaterina1,Tretyakova Maria1,Zelchan Roman13,Schulga Alexey14,Konovalova Elena14,Vorobyeva Anzhelika5ORCID,Belousov Mikhail12,Orlova Anna5ORCID,Tolmachev Vladimir6,Deyev Sergey14

Affiliation:

1. Research Centrum for Oncotheranostics, Research School of Chemistry and Applied Biomedical Sciences, Tomsk Polytechnic University, 634050 Tomsk, Russia

2. Department of Pharmaceutical Analysis, Siberian State Medical University, 634050 Tomsk, Russia

3. Department of Nuclear Medicine, Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, 634009 Tomsk, Russia

4. Molecular Immunology Laboratory, Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia

5. Department of Medicinal Chemistry, Uppsala University, 751 23 Uppsala, Sweden

6. Department of Immunology, Genetics and Pathology, Uppsala University, 75185 Uppsala, Sweden

Funder

Tomsk Polytechnic University

Cancerfonden

Publisher

American Chemical Society (ACS)

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