Toward Successful Cyclodextrin Based Solubility-Enabling Formulations for Oral Delivery of Lipophilic Drugs: Solubility–Permeability Trade-Off, Biorelevant Dissolution, and the Unstirred Water Layer-Reference-Cited by-同舟云学术

Toward Successful Cyclodextrin Based Solubility-Enabling Formulations for Oral Delivery of Lipophilic Drugs: Solubility–Permeability Trade-Off, Biorelevant Dissolution, and the Unstirred Water Layer

Published:2017-05-24 Issue:6 Volume:14 Page:2138-2146
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Fine-Shamir Noa¹,Beig Avital¹,Zur Moran¹,Lindley David²,Miller Jonathan M.²,Dahan Arik¹^ORCID

Affiliation:

1. Department of Clinical Pharmacology, School of Pharmacy, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel

2. AbbVie Inc., North Chicago, Illinois 60064, United States

Funder

AbbVie

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.7b00275

Reference55 articles.

1. Self-nano-emulsifying drug delivery systems: an update of the biopharmaceutical aspects

2. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings 1PII of original article: S0169-409X(96)00423-1. The article was originally published in Advanced Drug Delivery Reviews 23 (1997) 3–25. 1

3. Integrating drug permeability with dissolution profile to develop IVIVC

4. Computational prediction of formulation strategies for beyond-rule-of-5 compounds

5. Biopharmaceutical classification of poorly soluble drugs with respect to “enabling formulations”

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