Preclinical Evaluation of a Companion Diagnostic Radiopharmaceutical, [18F]PSMA-1007, in a Subcutaneous Prostate Cancer Xenograft Mouse Model

Author:

Kim Su Bin12ORCID,Song In Ho2,Kim Seon Yoo3,Ko Hae Young3,Kil Hee Seup4,Chi Dae Yoon4,Giesel Frederik L.5,Kopka Klaus6789,Hoepping Alexander10,Chun Joong-Hyun3ORCID,Park Hyun Soo211,Yun Mijin3,Kim Sang Eun2111213

Affiliation:

1. Department of Applied Bioengineering, Graduate School of Convergence Science and Technology, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul08826, Korea

2. Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, 82 Gumi-ro, 173 Beon-gil, Bundang-gu, Seongnam13620, Korea

3. Department of Nuclear Medicine, Severance Hospital, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul03722, Korea

4. Research Institute of Radiopharmaceuticals, FutureChem Co. Ltd, Seoul04793, Korea

5. Department of Nuclear Medicine, Heinreich-Heine-University, University Hospital Duesseldorf, Duesseldorf40225, Germany

6. Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR) e.v., Bautzner Landstrasse 400, Dresden01328, Germany

7. Technische Universität Dresden, Faculty of Chemistry and Food Chemistry, School of Science, Dresden01069, Germany

8. National Center for Tumor Diseases (NCT) Dresden, University Hospital Carl Gustav Carus, Fetscherstraße 74, Dresden01307, Germany

9. German Cancer Consortium (DKTK), Partner Site Dresden, Dresden01307, Germany

10. Department of Medicinal Chemistry, ABX Advanced Biochemical Compounds GmbH, Radeberg1454, Germany

11. Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul08826, Korea

12. Advanced Institutes of Convergence Technology, 145 Gwanggyo-ro, Yeongtong-gu, Suwon16229, Korea

13. BIK Therapeutics Inc., 172 Dolma-ro, Bundang-gu, Seongnam13605, Korea

Funder

Bundesministerium f??r Bildung und Forschung

National Research Foundation of Korea

Seoul National University Bundang Hospital

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

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