Pharmacokinetic Considerations for Optimizing Inhaled Spray-Dried Pyrazinoic Acid Formulations

Author:

Yeshwante Shekhar B.1,Hanafin Patrick1,Miller Brittany K.2,Rank Laura2,Murcia Sebastian2,Xander Christian2,Annis Ayano2,Baxter Victoria K.3ORCID,Anderson Elizabeth J.3ORCID,Jermain Brian1,Konicki Robyn1,Schmalstig Alan A.2,Stewart Ian4,Braunstein Miriam2,Hickey Anthony J.45,Rao Gauri G.1ORCID

Affiliation:

1. Division of Pharmacotherapy and Experimental Therapeutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States

2. Department of Microbiology, UNC School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States

3. Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States

4. Technology Advancement and Commercialization, RTI International, Research Triangle Park, North Carolina 27709, United States

5. Division of Pharmacoengineering and Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States

Funder

National Institute of Allergy and Infectious Diseases

Potts Family Foundation

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

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