Immuno-PET Imaging and Pharmacokinetics of an Anti-CEA scFv-based Trimerbody and Its Monomeric Counterpart in Human Gastric Carcinoma-Bearing Mice-Reference-Cited by-同舟云学术

Immuno-PET Imaging and Pharmacokinetics of an Anti-CEA scFv-based Trimerbody and Its Monomeric Counterpart in Human Gastric Carcinoma-Bearing Mice

Published:2019-02-06 Issue:3 Volume:16 Page:1025-1035
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Rios Xabier¹,Compte Marta²,Gómez-Vallejo Vanessa³,Cossío Unai¹^ORCID,Baz Zuriñe¹,Morcillo Miguel Ángel⁴,Ramos-Cabrer Pedro⁵⁶^ORCID,Alvarez-Vallina Luis⁷,Llop Jordi¹^ORCID

Affiliation:

1. Radiochemistry and Nuclear Imaging Group, CIC biomaGUNE, 20014 San Sebastián, Guipúzcoa, Spain

2. Molecular Immunology Unit, Hospital Universitario Puerta de Hierro Majadahonda, Manuel de Falla 1, 28222 Majadahonda, Madrid, Spain

3. Radiochemistry Platform, CIC biomaGUNE, 20014 San Sebastián, Guipúzcoa, Spain

4. Biomedical Applications of Radioisotopes and Pharmacokinetics Unit, CIEMAT, 28040 Madrid, Spain

5. Magnetic Resonance Imaging Group, CIC biomaGUNE, 20014 San Sebastián, Guipúzcoa Spain

6. Ikerbasque, The Basque Foundation for Science, 48013 Bilbao, Spain

7. Immunotherapy and Cell Engineering Group, Department of Engineering, Aarhus University, Gustav WiedsVej 10, 8000 C Aarhus, Denmark

Funder

Sundhed og Sygdom, Det Frie Forskningsr?d

Ministerio de Ciencia e Innovaci?n

Secretar?a de Estado de Investigaci?n, Desarrollo e Innovaci?n

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.8b01006

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