Investigation and Mathematical Description of the Real Driving Force of Passive Transport of Drug Molecules from Supersaturated Solutions-Reference-Cited by-同舟云学术

Investigation and Mathematical Description of the Real Driving Force of Passive Transport of Drug Molecules from Supersaturated Solutions

Published:2016-09-27 Issue:11 Volume:13 Page:3816-3826
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Borbás Enikő¹,Sinkó Bálint²,Tsinman Oksana²,Tsinman Konstantin²,Kiserdei Éva¹,Démuth Balázs¹,Balogh Attila¹,Bodák Brigitta¹,Domokos András¹,Dargó Gergő¹³,Balogh György T.³,Nagy Zsombor K.¹

Affiliation:

1. Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, Budapest 1111, Hungary

2. Pion Inc., Billerica, Massachusetts 01821, United States

3. Compound Profiling Laboratory, Gedeon Richter Plc., Budapest 1103, Hungary

Funder

Magyar Tudományos Akadémia

Országos Tudományos Kutatási Alapprogramok

European Social Fund

Magyarország Kormánya

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.6b00613

Reference58 articles.

1. The influence of lead discovery strategies on the properties of drug candidates

2. Drug-like properties and the causes of poor solubility and poor permeability

3. FDA. Waiver of In Vivo Bioavailability and Bioequivalence Studies for Immediate-Release Solid Oral Dosage Forms Based on a Biopharmaceutics Classification System Guidance for Industry. 2015.

4. In vitro models to evaluate the permeability of poorly soluble drug entities: Challenges and perspectives

5. Impact of Solubilizing Additives on Supersaturation and Membrane Transport of Drugs

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