Human Immortalized Cell-Based Blood–Brain Barrier Spheroid Models Offer an Evaluation Tool for the Brain Penetration Properties of Macromolecules-Reference-Cited by-同舟云学术

Human Immortalized Cell-Based Blood–Brain Barrier Spheroid Models Offer an Evaluation Tool for the Brain Penetration Properties of Macromolecules

Published:2022-06-29 Issue:8 Volume:19 Page:2754-2764
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Kitamura Keita¹²,Okamoto Ayaka²,Morio Hanae²,Isogai Ryuto²,Ito Ryo³^ORCID,Yamaura Yoshiyuki⁴,Izumi Saki⁵^ORCID,Komori Takafumi⁵,Ito Shingo⁶,Ohtsuki Sumio⁶^ORCID,Akita Hidetaka¹^ORCID,Furihata Tomomi²^ORCID

Affiliation:

1. Laboratory of DDS Design and Drug Disposition, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba 260-8670, Japan

2. Laboratory of Clinical Pharmacy & Experimental Therapeutics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Tokyo 192-0392, Japan

3. Research Center of Neurology, Ono Pharmaceutical Co., Ltd., Osaka 618-8585, Japan

4. Pharmacokinetic Research Laboratories, Ono Pharmaceutical Co., Ltd., Osaka 618-8585, Japan

5. Global Drug Metabolism and Pharmacokinetics, Tsukuba Research Laboratories, Eisai Co. Ltd., 5-1-3 Tokodai, Ibaraki 300-2635, Japan

6. Department of Pharmaceutical Microbiology, Faculty of Life Sciences, Kumamoto University, Kumamoto 862-0973, Japan

Funder

Eisai

Japan Agency for Medical Research and Development

Japan Society for the Promotion of Science

Ono Pharmaceutical

Mochida Memorial Foundation for Medical and Pharmaceutical Research

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.2c00120

Reference33 articles.

1. Astrocyte–endothelial interactions at the blood–brain barrier

2. Functional morphology of the blood–brain barrier in health and disease

3. The Blood–Brain Barrier

4. Neurodegenerative diseases and effective drug delivery: A review of challenges and novel therapeutics

5. Antibody Approaches To Treat Brain Diseases

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Mathematical Analysis of Bio-nanofluid Flow over a Nonlinear Tapering Artery with Stenosis Conditions Using Cross Fluid Viscosity Model;BioNanoScience;2023-10-03

2. MPS for Blood Brain Barrier;YAKUGAKU ZASSHI;2023-01-01

3. Generation of a Human Conditionally Immortalized Cell-based Multicellular Spheroidal Blood-Brain Barrier Model for Permeability Evaluation of Macromolecules;BIO-PROTOCOL;2022