NGR-TNF Engineering with an N-Terminal Serine Reduces Degradation and Post-Translational Modifications and Improves Its Tumor-Targeting Activity-Reference-Cited by-同舟云学术

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NGR-TNF Engineering with an N-Terminal Serine Reduces Degradation and Post-Translational Modifications and Improves Its Tumor-Targeting Activity

Published:2020-08-17 Issue:10 Volume:17 Page:3813-3824
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Corti Angelo¹²,Gasparri Anna Maria²,Sacchi Angelina²,Colombo Barbara²,Monieri Matteo²,Rrapaj Eltjona²,Ferreri Andrés J. M.³,Curnis Flavio²^ORCID

Affiliation:

1. Università Vita-Salute San Raffaele, Milan 20132, Italy

2. Tumor Biology and Vascular Targeting Unit, Division of Experimental Oncology, IRCCS San Raffaele Scientific Institute, Milan 20132, Italy

3. Lymphoma Unit, Department of Onco-hematology, IRCCS San Raffaele Scientific Institute, Milan 20132, Italy

Funder

Associazione Italiana per la Ricerca sul Cancro

Ministero della Salute

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.0c00579

Reference44 articles.

1. Cancer Treatment by Targeted Drug Delivery to Tumor Vasculature in a Mouse Model

2. The neovasculature homing motif NGR: more than meets the eye

3. Treatment of hypoxia‐induced retinopathy with targeted proapoptotic peptidomimetic in a mouse model of disease

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