Metabolism of an Oxime-Linked Antibody Drug Conjugate, AGS62P1, and Characterization of Its Identified Metabolite
Author:
Affiliation:
1. Agensys Inc. an Affiliate of Astellas Pharma Inc., 1800 Stewart Street, Santa Monica, California 90404, United States
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Pharmaceutical Science,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.8b00225
Reference19 articles.
1. Antibody–Drug Conjugates (ADCs) for Personalized Treatment of Solid Tumors: A Review
2. Expression of the hematopoietic growth factor receptor FLT3 (STK- 1/Flk2) in human leukemias
3. AN ANALYSIS OF THE SEQUENCES OF THE VARIABLE REGIONS OF BENCE JONES PROTEINS AND MYELOMA LIGHT CHAINS AND THEIR IMPLICATIONS FOR ANTIBODY COMPLEMENTARITY
4. Synthesis of site-specific antibody-drug conjugates using unnatural amino acids
5. Strategies and challenges for the next generation of antibody–drug conjugates
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