Amorphous Drug–Polymer Salts: Maximizing Proton Transfer to Enhance Stability and Release-Reference-Cited by-同舟云学术

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Amorphous Drug–Polymer Salts: Maximizing Proton Transfer to Enhance Stability and Release

Published:2023-01-20 Issue:2 Volume:20 Page:1347-1356
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Neusaenger Amy Lan¹^ORCID,Yao Xin¹^ORCID,Yu Junguang¹^ORCID,Kim Soojin¹,Hui Ho-Wah²,Huang Lian²,Que Chailu²,Yu Lian¹³^ORCID

Affiliation:

1. School of Pharmacy, University of Wisconsin, Madison, Wisconsin 53705, United States

2. Drug Product Development, Bristol Myers Squibb, Summit, New Jersey 07901, United States

3. Department of Chemistry, University of Wisconsin, Madison, Wisconsin 53706, United States

Funder

Bill and Melinda Gates Foundation

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.2c00942

Reference28 articles.

1. Solubility advantage of amorphous pharmaceuticals: I. A thermodynamic analysis

2. Enhanced Bioavailability of a Poorly Soluble VR1 Antagonist Using an Amorphous Solid Dispersion Approach: A Case Study

3. The use of amorphous solid dispersions: A formulation strategy to overcome poor solubility and dissolution rate

4. Amorphous solid dispersions and nano-crystal technologies for poorly water-soluble drug delivery

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4. Effects of Polymers on Cocrystal Growth in a Drug–Drug Coamorphous System: Relations between Glass-to-Crystal Growth and Surface-Enhanced Crystal Growth;Molecular Pharmaceutics;2024-05-31

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